Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18637090 | 0.90 | ABCB1 (0.56) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL9007850 | 0.86 | USP2 (0.59) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20192151 | 0.81 | MEN1 (0.45) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494783 | 0.81 | ABCB1 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494880 | 0.80 | ABCB1 (0.45) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL17109310 | 0.80 | ABCB1 (0.44) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL17109312 | 0.79 | FPR2 (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14046505 | 0.79 | ABCB1 (0.55) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494774 | 0.79 | USP2 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12763951 | 0.79 | POLB (0.50) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981934-B2 | Enzyme-specific fluorescent compound capable of being retained in cells | THE UNIVERSITY OF TOKYO (JP) | 2018-05-29 | — | — | US | disclosed |