Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12840678 | 0.83 | KMT2A (0.34) | ALDH1A1HPGDHSD17B10KMT2ATDP1 | |
| SCHEMBL19287187 | 0.82 | CYP1A2 (0.38) | ALDH1A1HPGDHSD17B10CYP1A2KMT2A | |
| SCHEMBL18739478 | 0.81 | KMT2A (0.33) | ALDH1A1HPGDHSD17B10KMT2ATDP1 | |
| SCHEMBL19538511 | 0.68 | CYP1A2 (0.39) | ALDH1A1HPGDCYP1A2KMT2ATDP1 | |
| SCHEMBL16708654 | 0.67 | HCAR3 (0.36) | ALDH1A1HPGDHSD17B10HCAR3GRM5 | |
| SCHEMBL20705465 | 0.66 | CYP1A2 (0.37) | ALDH1A1HPGDCYP1A2KMT2ATDP1 | |
| SCHEMBL12674552 | 0.65 | CDK5 (0.39) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL11188433 | 0.63 | HSD17B10 (0.40) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL11095698 | 0.62 | CDK5 (0.32) | ALDH1A1KMT2ATDP1MEN1L3MBTL1 | |
| SCHEMBL5516186 | 0.58 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982016-B2 | NPR-B agonists | SHIRE ORPHAN THERAPIES GMBH (DE) | 2018-05-29 | — | — | US | disclosed |