SCHEMBL20192908

SCHEMBL20192908

CCNC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.49
GSR P00390 1/20 0.48
NOD1 Q9Y239 3/20 0.48
OTC P00480 1/20 0.47
EPHX2 P34913 1/20 0.46
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
EPHX1 P07099 4/20 0.46
ARG1 P05089 3/20 0.44
ARG2 P78540 3/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863618 0.88 EPHX1 (0.63) DPP7NOD1EPHX2GNAI3GNAO1
SCHEMBL8747462 0.88 EPHX1 (0.63) DPP7NOD1EPHX2GNAI3GNAO1
SCHEMBL20192642 0.84 GSR (0.60) DPP7GSROTCGNAI3GNAO1
SCHEMBL23129226 0.84 GSR (0.50) DPP7GSRNOD1OTCGNAI3
SCHEMBL30286002 0.83 DPP7 (0.46) DPP7GSRNOD1OTCGNAI3
SCHEMBL30302208 0.83 DPP7 (0.46) DPP7GSRNOD1OTCGNAI3
SCHEMBL9845026 0.82 GSR (0.52) DPP7GSROTCGNAI3GNAO1
SCHEMBL9845024 0.82 GSR (0.52) DPP7GSROTCGNAI3GNAO1
SCHEMBL22914459 0.81 GSR (0.43) DPP7GSRNOD1OTCARG1
SCHEMBL1423420 0.81 MEN1 (0.61) DPP7GSRNOD1OTCGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981908-B2 Amino acid derivatives MEDIMMUNE LIMITED (GB) 2018-05-29 US disclosed