SCHEMBL2863618

SCHEMBL2863618

CCCCCCCCCCCCCCCCCCNC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.63
GNAI3 P08754 1/20 0.60
GNAO1 P09471 1/20 0.60
GNAI1 P63096 1/20 0.60
DPP7 Q9UHL4 2/20 0.60
NOD1 Q9Y239 4/20 0.56
RRM1 P23921 1/20 0.55
GRIK1 P39086 2/20 0.54
GRIK2 Q13002 2/20 0.54
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
EPHX2 P34913 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747462 1.00 EPHX1 (0.63) EPHX1GNAI3GNAO1GNAI1DPP7
SCHEMBL20192908 0.88 DPP7 (0.49) EPHX1GNAI3GNAO1GNAI1DPP7
SCHEMBL10615527 0.86 GRIK1 (0.57) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL4385896 0.86 GRIK1 (0.57) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL1243678 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL17392871 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL308741 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL15986104 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL2386271 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1
SCHEMBL13855547 0.86 NOD1 (0.74) GNAI3GNAO1GNAI1DPP7NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US disclosed
EP-1515684-B1 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM OREAL (FR) 2010-05-19 EP disclosed
CN-100581529-C Care and/or make-up cosmetic composition structured with silicone polymers and organogelators in rigid form OREAL 2010-01-20 CN disclosed
EP-1676556-A2 Cosmetic composition containing a polyorganosiloxane polymer L'OREAL (FR) 2006-07-05 EP disclosed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US disclosed
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN disclosed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 EP disclosed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 WO disclosed