Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | OTC | P00480 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 6/20 | 0.43 |
| ▸ | NOS1 | P29475 | 5/20 | 0.43 |
| ▸ | NOS3 | P29474 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 3/20 | 0.40 |
| ▸ | ARG2 | P78540 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Nil SCHEMBL322091 | 0.82 | ARG2 (0.50) | GSROTCNOD1NOS2NOS1 | |
| L-Nil SCHEMBL934874 | 0.82 | ARG2 (0.50) | GSROTCNOD1NOS2NOS1 | |
| L-Nil SCHEMBL31540966 | 0.82 | ARG2 (0.50) | GSROTCNOD1NOS2NOS1 | |
| SCHEMBL14233369 | 0.82 | NOS2 (0.54) | GSRNOD1NOS2NOS1NOS3 | |
| SCHEMBL16577957 | 0.82 | NOS2 (0.54) | GSRNOD1NOS2NOS1NOS3 | |
| SCHEMBL20192908 | 0.81 | DPP7 (0.49) | GSROTCNOD1NOS2NOS1 | |
| L-Nil SCHEMBL7977021 | 0.81 | ARG2 (0.51) | GSROTCNOS2NOS1NOS3 | |
| L-Nil SCHEMBL7974005 | 0.81 | ARG2 (0.51) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL8065968 | 0.81 | NOS2 (0.50) | GSROTCNOD1NOS2NOS1 | |
| L-Nil SCHEMBL1321685 | 0.81 | ARG2 (0.51) | GSROTCNOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024935-A1 | Read Through Of Truncated Proteins In Premature Termination Codon Diseases Using An Optimized Genetic Codon Expansion System | PEKING UNIVERSITY (CN) | 2021-01-28 | — | — | US | disclosed |