Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20193154 | 0.90 | CHUK (0.37) | CHUK | |
| SCHEMBL20193152 | 0.90 | CHUK (0.39) | CHUK | |
| SCHEMBL19114436 | 0.87 | CHUK (0.38) | CHUKDYRK1ASCN5ASCN9A | |
| SCHEMBL16608646 | 0.87 | DGAT1 (0.36) | CHUKNFATC1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL20193179 | 0.87 | CREBBP (0.32) | CHUKGSK3BSCN5ASCN9A | |
| SCHEMBL19629559 | 0.86 | PDE4B (0.41) | NFATC1GSK3BDYRK1AMAP3K5SCN5A | |
| SCHEMBL19114590 | 0.86 | CHUK (0.34) | CHUKNFATC1GSK3BDYRK1AMAP3K5 | |
| SCHEMBL19114543 | 0.86 | CHUK (0.35) | CHUK | |
| SCHEMBL20193242 | 0.85 | CHUK (0.36) | CHUK | |
| SCHEMBL20193155 | 0.84 | CHUK (0.38) | CHUKNFATC1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |