Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608639 | 0.87 | PIM1 (0.39) | PIM1PIM3PIM2DYRK1AALK | |
| SCHEMBL19629548 | 0.86 | PIM1 (0.43) | PIM1PIM3PIM2 | |
| SCHEMBL20193261 | 0.82 | — | — | |
| SCHEMBL20193179 | 0.80 | CREBBP (0.32) | PIM1ALKCHUK | |
| SCHEMBL19114543 | 0.80 | CHUK (0.35) | CHUK | |
| SCHEMBL19114436 | 0.79 | CHUK (0.38) | PIM1PIM3PIM2DYRK1ACHUK | |
| SCHEMBL20193242 | 0.79 | CHUK (0.36) | CHUK | |
| SCHEMBL20193217 | 0.78 | DYRK1A (0.40) | DYRK1ACHUK | |
| SCHEMBL20193151 | 0.78 | CHUK (0.34) | DYRK1ACHUK | |
| SCHEMBL20193155 | 0.78 | CHUK (0.38) | DYRK1ACHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |