SCHEMBL201938

SCHEMBL201938

CC(=O)Nc1ccc(C=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
KDM4E B2RXH2 3/20 0.64
SMN1; SMN2 Q16637 4/20 0.61
HTT P42858 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
KMT2A Q03164 6/20 0.59
MEN1 O00255 4/20 0.59
MAPT P10636 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
CA12 O43570 1/20 0.59
BRD4 O60885 1/20 0.59
NR1I2 O75469 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
MB P02144 1/20 0.59
CYP1A1 P04798 1/20 0.59
CA3 P07451 1/20 0.59
CYP3A4 P08684 1/20 0.59
RARG P13631 1/20 0.59
TSHR P16473 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7802754 0.98 ALDH1A1 (0.62) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL6791371 0.94 SMN1; SMN2 (0.73) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL28348281 0.91 ALDH1A1 (0.64) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
Benzaldehyde SCHEMBL4562813 0.89 NAPRT (0.60) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL8702167 0.88 CYP2A6 (0.63) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL7941715 0.84 SMN1; SMN2 (0.64) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL10944710 0.84 SMN1; SMN2 (0.64) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL7941711 0.84 SMN1; SMN2 (0.64) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
Cyclopentanamine SCHEMBL7800383 0.83 KDM4E (0.53) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL861674 0.83 SMN1; SMN2 (0.84) ALDH1A1KDM4ESMN1; SMN2HTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192442-A Material for hydrophilic modification of polytetrafluoroethylene microporous membrane and preparation method thereof 浙江东大环境工程有限公司 2024-12-27 CN claimed
US-20240318325-A1 ELECTROCHEMICAL HYDROGENOLYSIS OF CARBONYL GROUPS IN ALDEHYDES AND KETONES USING ZINC CATHODES WISCONSIN ALUMNI RESEARCH FOUNDATION 2024-09-26 US claimed
CN-116102462-B Near infrared fluorescent probe responding to formaldehyde and preparation method and application thereof 南京林业大学 2024-09-06 CN claimed
CN-118373776-A Phenanthroimidazole aniline compound for detecting perfluorocarboxylic acid and analogues thereof, and preparation method and application thereof 中国科学院生态环境研究中心 2024-07-23 CN claimed
CN-118005552-A Two-photon fluorescent probe for selectively recognizing cysteine and preparation and application thereof 武汉工程大学 2024-05-10 CN claimed
US-11952383-B1 Aza-podophyllotoxin analogues as potential anti-cancer agents King Faisal University (SA) 2024-04-09 US claimed
CN-117362197-A Double-cyano stilbene fluorescent probe and synthetic method and application thereof 福建师范大学 2024-01-09 CN claimed
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN claimed
CN-116462648-A Near-infrared small molecule fluorescent probe and preparation method and application thereof 海南医学院 2023-07-21 CN claimed
CN-116102462-A Near infrared fluorescent probe responding to formaldehyde and preparation method and application thereof 南京林业大学 2023-05-12 CN claimed
US-4549025-A REACTING WITH CHLORITES MONTEDISON S.P.A. (IT) 1985-10-22 US claimed
EP-0151593-A1 ENZYME DERIVATIVES. BEECHAM GROUP PLC (GB) 1985-08-21 EP claimed
WO-1985000521-A1 ENZYME DERIVATIVES BEECHAM GROUP P.L.C. (GB) 1985-02-14 WO claimed
US-4483861-A Antihypertensive sulfur-containing compounds SANTEN PHARMACEUTICAL CO., LTD. (JP) 1984-11-20 US claimed
EP-0092830-A2 Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application CIBA-GEIGY AG (CH) 1983-11-02 EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4345072-A Process for the production of 5-arylidene hydantoins (B) DEGUSSA AG (DE) 1982-08-17 US claimed
US-4254035-A BY REACTING GLYCINE AND AN AROMATIC ALDEHYDE IN THE PRESENCE OF ACETIC ANHYDRIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-03 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4053608-A 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED SANKYO COMPANY LIMITED (JA) 1977-10-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952383-B1 Aza-podophyllotoxin analogues as potential anti-cancer agents TOP2A, SDAD1, PLEC ALDH1A1 1852/4885KDM4E 1602/4885SMN1; SMN2 4091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.