SCHEMBL2019383

SCHEMBL2019383

CCCCCCCCCCC1OC1C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
EPHX1 P07099 1/20 0.43
SPHK1 Q9NYA1 4/20 0.42
SPHK2 Q9NRA0 3/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
FUCA1 P04066 1/20 0.41
EBP Q15125 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
GBA1 P04062 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11591222 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL6143422 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL11589442 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL7495822 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL6656106 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL23231188 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL11796515 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL284340 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL17010813 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR
SCHEMBL51664 1.00 ALDH1A1 (0.46) ALDH1A1EPHX1SPHK1SPHK2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108391435-B High molecular weight hydrophobic polyols 陶氏环球技术有限责任公司 2021-01-08 CN disclosed
US-10787619-B2 Effective novel polymeric additive for inhibiting napthenic acid corrosion and method of using the same DORF KETAL CHEMICALS (INDIA) PRIVATE LIMITED (IN) 2020-09-29 US disclosed
EP-3374409-B1 HIGH MOLECULAR WEIGHT HYDROPHOBIC POLYOL DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-09 EP disclosed
US-10662276-B2 High molecular weight hydrophobic polyol DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-26 US disclosed
EP-2326676-B1 AN EFFECTIVE NOVEL POLYMERIC ADDITIVE FOR INHIBITING NAPTHENIC ACID CORROSION AND METHOD OF USING THE SAME DORF KETAL CHEMICALS I PRIVATE LTD (IN) 2020-02-26 EP disclosed
US-20180346637-A1 High Molecular Weight Hydrophobic Polyol DOW GLOBAL TECHNOLOGIES LLC 2018-12-06 US disclosed
EP-3374409-A1 HIGH MOLECULAR WEIGHT HYDROPHOBIC POLYOL Dow Global Technologies LLC (US) 2018-09-19 EP disclosed
EP-3039008-B1 ETHERAMINES BASED ON ALKOXYLATED GLYCERINE OR TRIMETHYLOLPROPANE. BASF SE (DE) 2018-08-08 EP disclosed
US-9932293-B2 Etheramines based on alkoxylated glycerine or trimethylolpropane BASF SE (DE) 2018-04-03 US disclosed
WO-2017083380-A1 HIGH MOLECULAR WEIGHT HYDROPHOBIC POLYOL DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-18 WO disclosed
US-20160251304-A1 ETHERAMINES BASED ON ALKOXYLATED GLYCERINE OR TRIMETHYLOLPROPANE BASF SE (DE) 2016-09-01 US disclosed
EP-3039008-A1 ETHERAMINES BASED ON ALKOXYLATED GLYCERINE OR TRIMETHYLOLPROPANE. BASF SE (DE) 2016-07-06 EP disclosed
WO-2015028193-A1 ETHERAMINES BASED ON ALKOXYLATED GLYCERINE OR TRIMETHYLOLPROPANE. BASF SE (DE) 2015-03-05 WO disclosed
EP-2842936-A1 Etheramines based on alkoxylated glycerine or trimethylolpropane. BASF SE (DE) 2015-03-04 EP disclosed
CN-102712871-A Lubricating oil composition JX NIPPON OIL & ENERGY CORP 2012-10-03 CN disclosed
CN-102533392-A Working fluid composition for refrigerator machine and refrigerating machine oil JX NIPPON OIL & ENERGY CORP 2012-07-04 CN disclosed
US-20110160405-A1 EFFECTIVE NOVEL POLYMERIC ADDITIVE FOR INHIBITING NAPTHENIC ACID CORROSION AND METHOD OF USING THE SAME DORF KETAL CHEMICALS (1) PRIVATE LIMITED (IN) 2011-06-30 US disclosed
EP-2326676-A1 AN EFFECTIVE NOVEL POLYMERIC ADDITIVE FOR INHIBITING NAPTHENIC ACID CORROSION AND METHOD OF USING THE SAME Dorf Ketal Chemicals (I) Private Limited (IN) 2011-06-01 EP disclosed
WO-2010023628-A1 AN EFFECTIVE NOVEL POLYMERIC ADDITIVE FOR INHIBITING NAPTHENIC ACID CORROSION AND METHOD OF USING THE SAME DORF KETAL CHEMICALS (I) PVT. LTD. (IN) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160251304-A1 ETHERAMINES BASED ON ALKOXYLATED GLYCERINE OR TRIMETHYLOLPROPANE GK, CERT1, SGMS1 ALDH1A1 1834/4885EPHX1 75/4885SPHK1 63/4885
US-20110160405-A1 EFFECTIVE NOVEL POLYMERIC ADDITIVE FOR INHIBITING NAPTHENIC ACID CORROSION AND METHOD OF USING THE SAME NAPEPLD, SQLE, NAPA ALDH1A1 432/4885EPHX1 711/4885SPHK1 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.