Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415464 | 0.86 | ALDH1A1 (0.57) | HPGDHSD17B10PTPRBMAPTNPSR1 | |
| SCHEMBL7620537 | 0.79 | HPGD (0.55) | HPGDHSD17B10PTPRBMAPTALDH1A1 | |
| SCHEMBL2902943 | 0.79 | ALDH1A1 (0.63) | HPGDHSD17B10PTPRBALDH1A1LCK | |
| Hydrochloric Acid SCHEMBL9029309 | 0.77 | LMNA (0.46) | MAPTNPSR1ALDH1A1LMNAPOLB | |
| SCHEMBL20857699 | 0.77 | LMNA (0.56) | HPGDHSD17B10PTPRBMAPTALDH1A1 | |
| SCHEMBL22430515 | 0.75 | HSD17B10 (0.51) | HPGDHSD17B10PTPRBMAPTALDH1A1 | |
| SCHEMBL3600382 | 0.75 | HPGD (0.51) | HPGDHSD17B10PTPRBMAPTALDH1A1 | |
| SCHEMBL22430520 | 0.75 | HPGD (0.51) | HPGDHSD17B10PTPRBALDH1A1LCK | |
| SCHEMBL1601877 | 0.75 | ALDH1A1 (0.53) | HPGDHSD17B10PTPRBMAPTALDH1A1 | |
| SCHEMBL18622118 | 0.74 | ALDH1A1 (0.50) | HPGDHSD17B10PTPRBALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |