Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | NNMT | P40261 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771982 | 0.89 | CA12 (0.53) | CA12CA1CA2CA3CA4 | |
| SCHEMBL14453581 | 0.84 | CA12 (0.44) | CA12CA1CA2CA3CA4 | |
| SCHEMBL6748636 | 0.83 | SIRT3 (0.46) | NNMTPOLBALDH1A1LMNAMAPT | |
| SCHEMBL11479346 | 0.83 | CA12 (0.59) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5166000 | 0.81 | ALDH1A1 (0.41) | KMT2APOLBALDH1A1MAPTCASP1 | |
| SCHEMBL31124522 | 0.80 | CA12 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL31124523 | 0.80 | CA12 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10628886 | 0.79 | ALDH1A1 (0.50) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10630827 | 0.79 | SMN1; SMN2 (0.35) | KMT2APOLBALDH1A1MAPTKDM4E | |
| SCHEMBL4639550 | 0.78 | CA12 (0.61) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327017-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Merck Patent GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |