SCHEMBL2019491

SCHEMBL2019491

C=CC(=O)OC(C)(CC)O[PH](=O)O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.37
TSHR P16473 7/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27986277 0.81 THRB (0.41) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2014874 0.80 THRB (0.38) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2014408 0.79 THRB (0.33) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28797570 0.78 THRB (0.39) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1804633 0.77 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2018530 0.75 ALDH1A1 (0.34) THRBTSHRALDH1A1
SCHEMBL15841862 0.75 THRB (0.37) THRBTSHRHPGDALDH1A1TP53
SCHEMBL865173 0.75 THRB (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28231205 0.74 THRB (0.36) THRBTSHRHPGDALDH1A1TP53
SCHEMBL16862851 0.73 THRB (0.38) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110160400-A1 Phosphoric and Acrylic Copolymer Resin Having Excellent Transparency and Flame Retardancy and Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20110160400-A1 Phosphoric and Acrylic Copolymer Resin Having Excellent Transparency and Flame Retardancy and Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2011-06-30 US disclosed