Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183756 | 0.91 | TP53 (0.38) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL20183695 | 0.83 | TP53 (0.39) | TP53POLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20183790 | 0.82 | TP53 (0.40) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL21549481 | 0.82 | RORC (0.39) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL20183517 | 0.81 | RXFP1 (0.40) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL21474026 | 0.81 | MAPT (0.41) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL20354318 | 0.80 | KDM4E (0.42) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL20183659 | 0.80 | RXRA (0.37) | TP53POLBMAPTRORCALDH1A1 | |
| SCHEMBL20183835 | 0.79 | KDM4E (0.35) | TP53POLBMAPTSMN1; SMN2RORC | |
| SCHEMBL20183702 | 0.79 | RORC (0.52) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |