Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183684 | 0.79 | TP53 (0.42) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183547 | 0.75 | GAA (0.47) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20354266 | 0.73 | PRKDC (0.54) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183597 | 0.72 | GAA (0.46) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183617 | 0.71 | ALDH1A1 (0.42) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183560 | 0.71 | TP53 (0.44) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183852 | 0.71 | PRKDC (0.47) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20354153 | 0.70 | KMT2A (0.46) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183652 | 0.70 | ALDH1A1 (0.40) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL20183859 | 0.70 | RORC (0.42) | KDM4EHPGDSMN1; SMN2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |