Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183776 | 0.89 | KMT2A (0.61) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20183828 | 0.83 | HIF1A (0.42) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20354153 | 0.79 | KMT2A (0.46) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20183732 | 0.77 | ENPP2 (0.47) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20183704 | 0.77 | MAPT (0.48) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL21473965 | 0.77 | MAPT (0.51) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL23253945 | 0.76 | MAPT (0.45) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL21549485 | 0.76 | MAPT (0.47) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20183715 | 0.75 | HIF1A (0.43) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL20195131 | 0.74 | ALDH1A1 (0.44) | MEN1MAPTKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |