SCHEMBL20195251

SCHEMBL20195251

c1sc(C2CCNCC2)nc1C1=NCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.52
BAZ2A Q9UIF9 3/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
AOC3 Q16853 1/20 0.38
HRH4 Q9H3N8 1/20 0.35
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
FAAH O00519 1/20 0.31
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19510349 0.81 HPGDS (0.47) HPGDSBAZ2AMEN1KMT2ANPC1
SCHEMBL4265265 0.76 HPGDS (0.61) HPGDSBAZ2AMEN1KMT2ANPC1
SCHEMBL2297392 0.76 HPGDS (0.78) HPGDSBAZ2AMEN1KMT2ANPC1
Bromide SCHEMBL2973216 0.75 HPGDS (0.76) HPGDSBAZ2AMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL3768256 0.75 HPGDS (0.76) HPGDSBAZ2AMEN1KMT2ANPC1
Bromide SCHEMBL2984301 0.75 HPGDS (0.60) HPGDSBAZ2AMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL1653092 0.75 HPGDS (0.76) HPGDSBAZ2AMEN1KMT2ANPC1
SCHEMBL4259512 0.74 HPGDS (0.59) HPGDSBAZ2AMEN1KMT2ANPC1
SCHEMBL4262100 0.74 HPGDS (0.59) HPGDSBAZ2AMEN1KMT2ANPC1
SCHEMBL3772350 0.74 HPGDS (0.59) HPGDSBAZ2AMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609094-B1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER IP GMBH (DE) 2018-05-30 EP disclosed