Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082081 | 0.92 | CA1 (0.48) | PTGIRL3MBTL1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL21613789 | 0.84 | ALDH1A1 (0.53) | PTGIRL3MBTL1ALDH1A1HRH3KDM4E | |
| SCHEMBL20291411 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2TP53HPGDMAPTKDM4E | |
| SCHEMBL24937730 | 0.83 | SMN1; SMN2 (0.51) | L3MBTL1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL23178944 | 0.82 | HPGD (0.46) | PTGIRL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12673074 | 0.82 | POLB (0.43) | PTGIRHPGDMAPTCA12CA1 | |
| SCHEMBL23178665 | 0.80 | KDM1A (0.43) | PTGIRCA12CA1CA2CA7 | |
| SCHEMBL18583232 | 0.77 | HPGD (0.43) | SMN1; SMN2ALDH1A1HPGDMAPTHRH3 | |
| SCHEMBL23863299 | 0.76 | DRD3 (0.58) | LTA4H | |
| SCHEMBL18583190 | 0.75 | HPGD (0.41) | PTGIRSMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327021-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | Yangji Chemical Co., Ltd. (KR) | 2018-05-30 | — | — | EP | disclosed |