Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377328 | 0.83 | OPRM1 (0.43) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL26079704 | 0.82 | RAB9A (0.53) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL19986858 | 0.81 | ADRB1 (0.52) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL24894095 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL21613881 | 0.80 | SMN1; SMN2 (0.33) | HPGDALDH1A1HRH3RAB9ASMN1; SMN2 | |
| SCHEMBL19478738 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL26242517 | 0.79 | NPC1 (0.48) | HPGDALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL19274519 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL15721254 | 0.77 | MAPK1 (0.44) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL19903214 | 0.77 | HPGD (0.39) | HPGDALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017034245-A1 | JANUS KINASE 1 SELECTIVE INHIBITOR AND PHARMACEUTICAL USE THEREOF | 양지화학 주식회사 | 2017-03-02 | — | — | WO | disclosed |