Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22038783 | 0.88 | HTR7 (0.47) | HTR7HTR1ATAAR1GABRA5 | |
| SCHEMBL22038668 | 0.84 | SCN9A (0.37) | HTR7GRM5GABRA5 | |
| SCHEMBL20845022 | 0.79 | TAAR1 (0.36) | HTR1ATAAR1 | |
| SCHEMBL22059405 | 0.75 | TP53 (0.35) | HTR1ATAAR1 | |
| SCHEMBL22037272 | 0.75 | HTR7 (0.41) | HTR7 | |
| SCHEMBL20195570 | 0.73 | TAAR1 (0.35) | HTR1ATAAR1 | |
| SCHEMBL20195478 | 0.73 | GABRA5 (0.38) | CYP11B1CYP11B2HTR7GRM5GABRA5 | |
| SCHEMBL20195500 | 0.72 | HTT (0.33) | HTR1ATAAR1 | |
| SCHEMBL18831504 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL22038196 | 0.72 | HTR7 (0.49) | HTR7HTR1AGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |