Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091660 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL18831391 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL476880 | 0.68 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL20120182 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL3726711 | 0.67 | LMNA (0.40) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11875028 | 0.67 | MEN1 (0.43) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL2097529 | 0.67 | MEN1 (0.46) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9500120 | 0.66 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL2091657 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL112040 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |