SCHEMBL2019550

SCHEMBL2019550

C=CC(=O)OCC(CC)(CC)O[PH](=O)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 7/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18378267 0.90 THRB (0.46) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL29376011 0.82 ALDH1A1 (0.52) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL9921533 0.80 ALDH1A1 (0.50) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL17933323 0.78 THRB (0.45) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL11869600 0.76 THRB (0.46) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL22195186 0.76 THRB (0.46) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL2015804 0.76 THRB (0.41) THRBALDH1A1TSHR
SCHEMBL3062833 0.75 THRB (0.45) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL17923925 0.75 THRB (0.45) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL28389134 0.74 ALDH1A1 (0.57) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087128-B1 FLAME-RETARDANT COPOLYMERS OF DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHATE OR DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHONATE MONOMERS AND POLYMER FOAMS BASED MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-11 EP claimed
US-20160304692-A1 FLAME-RETARDANT COPOLYMERS OF DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHATE OR DIALKYL (METH)ACRYLOYLOXYALKYL PHOSPHONATE MONOMERS AND POLYMER FOAMS BASED MADE THEREFROM THE DOW CHEMICAL COMPANY 2016-10-20 US claimed
US-20110160400-A1 Phosphoric and Acrylic Copolymer Resin Having Excellent Transparency and Flame Retardancy and Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2011-06-30 US disclosed