Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1916615 | 0.84 | POLB (0.56) | CA1CA2KDM4EPOLBMEN1 | |
| SCHEMBL21177278 | 0.83 | MAPT (0.59) | CA1CA2KDM4EPOLBMEN1 | |
| SCHEMBL11273760 | 0.81 | KDM4E (0.65) | CA1CA2KDM4EPOLBMEN1 | |
| SCHEMBL3732414 | 0.81 | ALDH1A1 (0.44) | KDM4EP2RY14POLBMEN1KMT2A | |
| SCHEMBL6038006 | 0.81 | NPC1 (0.59) | KDM4EPOLBMEN1KMT2AMAPT | |
| SCHEMBL12227565 | 0.79 | MAPT (0.47) | KDM4EPOLBMEN1KMT2AMAPT | |
| SCHEMBL23081898 | 0.78 | MAOB (0.44) | KDM4EP2RY14POLBMEN1KMT2A | |
| SCHEMBL5681335 | 0.78 | POLB (0.69) | CA1CA2KDM4EPOLBMEN1 | |
| SCHEMBL6004364 | 0.78 | TP53 (0.68) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL12290189 | 0.78 | CA1 (0.57) | CA1CA2KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097097-B1 | ANTIBODIES, IN PARTICULAR HUMAN ANTIBODIES, THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2018-05-30 | — | — | EP | disclosed |