Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195627 | 0.86 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1KMT2AATMTDP1 | |
| SCHEMBL20195552 | 0.83 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1KMT2AATMLMNA | |
| SCHEMBL20195498 | 0.81 | SSTR4 (0.41) | ALDH1A1CNR1CNR2 | |
| SCHEMBL20195647 | 0.78 | KDM4E (0.44) | L3MBTL1ALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL20195585 | 0.72 | ATP4A (0.43) | ALDH1A1KMT2ATDP1SGMS2MAPK8 | |
| SCHEMBL20195598 | 0.72 | KMT2A (0.49) | L3MBTL1ALDH1A1KMT2AATMSGMS2 | |
| SCHEMBL30749508 | 0.72 | TDP1 (0.44) | L3MBTL1ALDH1A1KMT2ATDP1MAPK8 | |
| SCHEMBL29209338 | 0.72 | TDP1 (0.44) | L3MBTL1ALDH1A1KMT2ATDP1MAPK8 | |
| SCHEMBL23286656 | 0.71 | NPC1 (0.45) | L3MBTL1TDP1LMNASGMS2NPC1 | |
| SCHEMBL17788248 | 0.71 | MRGPRX4 (0.46) | ALDH1A1LMNAALOX15SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |