Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532721 | 0.83 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL5384431 | 0.83 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL22048825 | 0.82 | RAB9A (0.38) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL22062300 | 0.82 | PLK4 (0.38) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL14138287 | 0.81 | HRH4 (0.42) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL29462567 | 0.81 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL5388939 | 0.80 | RAB9A (0.41) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20764391 | 0.80 | NPC1 (0.35) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL13311142 | 0.80 | KDR (0.43) | NPC1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL6518352 | 0.80 | KDR (0.55) | MEN1KMT2AKDM4EHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097097-B1 | ANTIBODIES, IN PARTICULAR HUMAN ANTIBODIES, THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2018-05-30 | — | — | EP | disclosed |