Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 6/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | BLVRB | P30043 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460298 | 0.84 | XDH (0.55) | CDC7DBF4LMNATRPM8XDH | |
| SCHEMBL1329734 | 0.84 | XDH (0.60) | CDC7DBF4LMNATRPM8XDH | |
| SCHEMBL2186240 | 0.82 | MEN1 (0.48) | CDC7DBF4LMNATRPM8TSHR | |
| SCHEMBL2186318 | 0.78 | CDC7 (0.55) | CDC7DBF4LMNATRPM8RAB9A | |
| SCHEMBL1316281 | 0.76 | CDC7 (0.77) | CDC7DBF4LMNATRPM8RAB9A | |
| SCHEMBL7892124 | 0.76 | CDC7 (0.55) | CDC7DBF4LMNATRPM8TSHR | |
| SCHEMBL29460318 | 0.76 | XDH (0.69) | RAB9ASMN1; SMN2XDHABCC4ABCB11 | |
| SCHEMBL3708460 | 0.75 | CDC7 (0.49) | CDC7DBF4LMNATRPM8RAB9A | |
| SCHEMBL19523342 | 0.75 | XDH (0.65) | CDC7DBF4LMNATRPM8RAB9A | |
| SCHEMBL20195691 | 0.74 | CDC7 (0.55) | CDC7DBF4LMNATRPM8XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927219-B1 | 2-ARYL SELENAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2018-05-30 | — | — | EP | disclosed |