Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19215317 | 1.00 | MEN1 (0.47) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL17887100 | 1.00 | MEN1 (0.47) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1476371 | 0.91 | TSHR (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL20195968 | 0.89 | LPAR2 (0.46) | ALDH1A1LPAR3LPAR2LPAR1 | |
| SCHEMBL23711161 | 0.88 | LMNA (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL20775408 | 0.85 | THRB (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1887792 | 0.85 | THRB (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28775036 | 0.85 | THRB (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| Ether SCHEMBL1476422 | 0.84 | TSHR (0.43) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL5961032 | 0.83 | LMNA (0.42) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938604-B1 | BETA-AMINO ESTER GAS HYDRATE INHIBITORS | NALCO CO (US) | 2018-05-30 | — | — | EP | disclosed |