Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15358153 | 0.84 | SCN4A (0.33) | CYP1A2CYP2C9CYP3A4CYP2A6AOC3 | |
| SCHEMBL20196350 | 0.81 | CYP1A2 (0.34) | CYP1A2CYP2C9IDO1MAPK1ALDH1A1 | |
| SCHEMBL15358120 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL20196059 | 0.75 | GRIN2D (0.38) | CYP1A2CYP2C9MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL16676160 | 0.73 | SMN1; SMN2 (0.33) | IDO1MAPK1ALDH1A1NPC1HPGD | |
| Trifluoroacetic Acid SCHEMBL16528638 | 0.72 | F2 (0.35) | ALDH1A1CYP3A4 | |
| SCHEMBL1196194 | 0.72 | DDR1 (0.40) | CYP1A2CYP2C9IDO1MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1016081 | 0.70 | AOC3 (0.42) | CYP1A2CYP2C9IDO1CYP3A4CYP2C19 | |
| SCHEMBL1764819 | 0.69 | ALDH1A1 (0.52) | CYP1A2CYP2C9IDO1ALDH1A1CYP3A4 | |
| SCHEMBL30812547 | 0.67 | ALDH1A1 (0.40) | CYP1A2CYP2C9IDO1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005739-B2 | Quinazolinone and isoquinolinone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2018-06-26 | — | — | US | disclosed |
| EP-2842939-B1 | BENZAMIDE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005739-B2 | Quinazolinone and isoquinolinone derivative | NQO2, SDHA, CYP3A5 | CYP1A2 59/4885CYP2C9 77/4885IDO1 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.