Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22783852 | 0.94 | CA1 (0.47) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL21335944 | 0.86 | CA1 (0.50) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL19075835 | 0.84 | KMT2A (0.62) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL23567648 | 0.84 | CA1 (0.54) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL19703283 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL19154503 | 0.82 | LTA4H (0.63) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2968894 | 0.82 | MEN1 (0.63) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL13411545 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL14274966 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL14274945 | 0.80 | S1PR4 (0.45) | CA1CA2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233909-A2 | ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | AbbVie Biotherapeutics Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3327027-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-07-07 | — | — | EP | disclosed |
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |