Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024366 | 0.92 | ACHE (0.52) | ACHEHIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL11149087 | 0.86 | ACHE (0.62) | ACHEALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL30003276 | 0.86 | ACHE (0.62) | ACHEALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL11428015 | 0.81 | TRPA1 (0.59) | ALDH1A1TRPA1CSNK2A1TDP1TP53 | |
| SCHEMBL2024877 | 0.80 | TUBB1 (0.47) | ACHEHIF1AEPAS1ALDH1A1TRPA1 | |
| SCHEMBL9656536 | 0.79 | HIF1A (0.46) | ACHEHIF1AEPAS1ALDH1A1CYP3A4 | |
| SCHEMBL29819084 | 0.77 | MAOB (0.64) | ACHEALDH1A1TRPA1MAOBTDP1 | |
| SCHEMBL29398758 | 0.77 | ACHE (0.62) | ACHEALDH1A1CYP3A4TRPA1TDP1 | |
| SCHEMBL92236 | 0.77 | MAOB (0.64) | ACHEALDH1A1TRPA1MAOBTDP1 | |
| SCHEMBL17629436 | 0.77 | MAOB (0.64) | ACHEALDH1A1TRPA1MAOBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073151-A2 | METHOD FOR THE TWO-STEP DYEING OF KERATIN FIBRES, BY APPLICATION OF A COMPOSITION COMPRISING A NAPHTALENE DERIVATIVE, THEN ALKALINE TREATMENT. | L'OREAL (FR) | 2011-06-23 | — | — | WO | claimed |
| EP-0850635-B1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | OREAL (FR) | 1999-07-14 | — | — | EP | claimed |
| EP-0850635-A1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | L'OREAL (FR) | 1998-07-01 | — | — | EP | claimed |
| EP-1749812-B1 | PROCESS FOR PRODUCING EASILY POLYMERIZABLE COMPOUND WITH A POLYMERIZATION INHIBITOR | MITSUBISHI CHEM CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| WO-2011073151-A2 | METHOD FOR THE TWO-STEP DYEING OF KERATIN FIBRES, BY APPLICATION OF A COMPOSITION COMPRISING A NAPHTALENE DERIVATIVE, THEN ALKALINE TREATMENT. | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |
| EP-1555993-B1 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2010-03-24 | — | — | EP | disclosed |
| EP-1555993-A2 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2005-07-27 | — | — | EP | disclosed |
| US-6821302-B2 | Oxidation color dye comprising a metal cyanate, free of ammonia, without the pungent odor of ammonia | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-11-23 | — | — | US | disclosed |
| US-6758866-B2 | AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-07-06 | — | — | US | disclosed |
| WO-2004039341-A2 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2004-05-13 | — | — | WO | disclosed |
| US-20040083557-A1 | Permanent coloring of hair using carbonate salts and bicarbonate salts and using percarbamic acid precursors | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-05-06 | — | — | US | disclosed |
| US-20040019980-A1 | One step hair coloring compositions using salts | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030135935-A1 | Enhanced color deposition for hair with sequestering agents | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-07-24 | — | — | US | disclosed |
| EP-0850635-B1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | OREAL (FR) | 1999-07-14 | — | — | EP | disclosed |
| US-5873910-A | IN FIRST STAGE APPLYING TO KERATIN FIBER A FIRST SOLUTION CONTAINING IN A DYEING MEDIUM A MANGANESE SALT AND/OR COMPLEX, IN SECOND STAGE, APPLYING TO THE HAIR A SOLUTION WHICH CONTAINS 4-SUBSTITUED NAPHTHOL/1-/ AND AN OXIDIZER | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| EP-0850635-A1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | L'OREAL (FR) | 1998-07-01 | — | — | EP | disclosed |
| EP-0297583-A2 | Photosensitive material and image forming method by use thereof | CANON KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |
| US-4460681-A | COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-07-17 | — | — | US | disclosed |