Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 5/20 | 0.32 |
| ▸ | CDC25B | P30305 | 5/20 | 0.32 |
| ▸ | EBP | Q15125 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161748 | 0.85 | PTPN1 (0.44) | PTPN1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL29398347 | 0.81 | CDC25A (0.51) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL332666 | 0.81 | CDC25A (0.51) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL29410405 | 0.81 | CDC25A (0.51) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL29527487 | 0.81 | CDC25A (0.51) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL15233192 | 0.69 | SLC10A1 (0.42) | PTPN1ACLYACACATOP2A | |
| SCHEMBL16488039 | 0.69 | SLC10A1 (0.42) | PTPN1ACLYACACATOP2A | |
| SCHEMBL14034589 | 0.69 | CDC25A (0.54) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL14116734 | 0.69 | CDC25A (0.54) | PTPN1CDC25ACDC25BEBP | |
| SCHEMBL29501285 | 0.68 | PTPN1 (0.58) | PTPN1ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986343-B1 | 8,9-EPOXYLANOSTANE COMPOUND LD-030 FOR THE TREATMENT OF CANCER VIA RHO PATHWAY | XIE WEIDONG (CA) | 2018-05-30 | — | — | EP | disclosed |