Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233192 | 1.00 | SLC10A1 (0.42) | SLC10A1PTPN1ACLYACACAGPBAR1 | |
| SCHEMBL28831684 | 0.86 | HMGCR (0.54) | SLC10A1ACLYACACAHMGCRUSP2 | |
| SCHEMBL17431782 | 0.86 | HSD11B1 (0.55) | SLC10A1PTPN1ACLYACACAGPBAR1 | |
| SCHEMBL4104338 | 0.85 | HMGCR (0.44) | SLC10A1PTPN1ACLYACACAGPBAR1 | |
| SCHEMBL24285051 | 0.84 | ACLY (0.54) | SLC10A1PTPN1ACLYACACAHMGCR | |
| SCHEMBL28161748 | 0.82 | PTPN1 (0.44) | PTPN1ACLYACACATOP2A | |
| SCHEMBL29510985 | 0.77 | ACLY (0.67) | ACLYACACAHIF1ACYP2C19HMGCR | |
| SCHEMBL12634185 | 0.77 | ACLY (0.67) | ACLYACACAHIF1ACYP2C19HMGCR | |
| SCHEMBL17428529 | 0.75 | HSD11B1 (0.44) | HSD11B1HSD11B2TOP2ACES2ACHE | |
| SCHEMBL13642557 | 0.73 | GPBAR1 (0.48) | PTPN1GPBAR1HIF1ACYP2C19TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957055-B2 | Aminoalkylsterol compounds with antitumoral and neuroprotective activity | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2015-02-17 | — | — | US | disclosed |