Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838921 | 1.00 | ACACB (0.43) | ACACBACACADRD2GAALMNA | |
| SCHEMBL31434500 | 0.89 | ACACB (0.43) | ACACBACACADRD2DGAT1KDM1A | |
| SCHEMBL31434553 | 0.83 | EPHX2 (0.43) | ACACBDRD2LMNADGAT1 | |
| SCHEMBL16838905 | 0.83 | GAA (0.49) | ACACBACACADRD2GAALMNA | |
| SCHEMBL16762066 | 0.81 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16762064 | 0.81 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9913805 | 0.81 | KDM1A (0.47) | SLC6A4SLC6A2SLC6A3KDM1A | |
| SCHEMBL9913881 | 0.81 | KDM1A (0.47) | SLC6A4SLC6A2SLC6A3KDM1A | |
| SCHEMBL23920510 | 0.76 | ATF4 (0.66) | ACACBACACALMNA | |
| SCHEMBL28724351 | 0.76 | ATF4 (0.66) | ACACBACACALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |