Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197146 | 1.00 | PDPK1 (0.54) | PDPK1MTORLTA4HEPHX2CYP4F2 | |
| SCHEMBL20197403 | 1.00 | PDPK1 (0.54) | PDPK1MTORLTA4HEPHX2CYP4F2 | |
| SCHEMBL20120322 | 0.82 | CTSL (0.44) | PDPK1MTORLTA4HEPHX2TSHR | |
| SCHEMBL20120320 | 0.82 | CTSL (0.44) | PDPK1MTORLTA4HEPHX2TSHR | |
| SCHEMBL8500194 | 0.81 | TSHR (0.57) | PDPK1MTORLTA4HTSHRALDH1A1 | |
| SCHEMBL12406769 | 0.81 | SSTR1 (0.49) | BCHESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL19599666 | 0.80 | LTA4H (0.49) | LTA4HEPHX2CYP4F2CYP4A11TSHR | |
| SCHEMBL2292522 | 0.80 | SSTR1 (0.56) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL12380725 | 0.80 | SSTR1 (0.56) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6889266 | 0.80 | SSTR1 (0.56) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847154-B1 | RADIOTRACER, IN PARTICULAR FOR CANCER | UNIV DE LORRAINE (FR) | 2018-05-30 | — | — | EP | disclosed |