Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197291 | 0.92 | KDM1A (0.60) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL3225623 | 0.87 | HPGD (0.55) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL7118324 | 0.82 | NPC1 (0.51) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL21516993 | 0.81 | NPC1 (0.51) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL20460485 | 0.81 | NPC1 (0.55) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL17373238 | 0.81 | HPGD (0.58) | HPGDSMN1; SMN2NPC1RAB9ATAS1R3 | |
| SCHEMBL16236985 | 0.81 | HPGD (0.54) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL16548437 | 0.81 | TAS1R3 (0.58) | HPGDKDM1AMAOASMN1; SMN2NPC1 | |
| SCHEMBL21090793 | 0.77 | HPGD (0.48) | HPGDNPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL3233932 | 0.77 | NPC1 (0.53) | HPGDSMN1; SMN2NPC1RAB9ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |