Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548435 | 0.81 | LMNA (0.40) | UTS2RDYRK1AMAPTSMN1; SMN2CRHR1 | |
| SCHEMBL14230025 | 0.79 | KCNH2 (0.40) | UTS2RDYRK1AMAPTSMN1; SMN2CRHR1 | |
| SCHEMBL14229881 | 0.79 | UTS2R (0.37) | UTS2RDYRK1AMAPTSMN1; SMN2CRHR1 | |
| SCHEMBL16544520 | 0.78 | UTS2R (0.36) | UTS2RDYRK1AMAPTSMN1; SMN2CRHR1 | |
| SCHEMBL16544497 | 0.76 | UTS2R (0.41) | UTS2RMAPTSMN1; SMN2CRHR1MEN1 | |
| SCHEMBL4995064 | 0.76 | UTS2R (0.39) | UTS2RMAPTSMN1; SMN2CRHR1LMNA | |
| SCHEMBL14229179 | 0.76 | UTS2R (0.39) | UTS2RMAPTSMN1; SMN2CRHR1LMNA | |
| SCHEMBL14229041 | 0.75 | UTS2R (0.38) | UTS2RMAPTSMN1; SMN2CRHR1LMNA | |
| SCHEMBL14200180 | 0.73 | UTS2R (0.38) | UTS2RMAPTSMN1; SMN2CRHR1LMNA | |
| SCHEMBL13403110 | 0.73 | CRHR1 (0.40) | DYRK1AMAPTSMN1; SMN2CRHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |