Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 17/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197221 | 0.91 | SREBF2 (0.55) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL22152727 | 0.86 | SREBF2 (0.43) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197320 | 0.85 | SREBF2 (0.44) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197312 | 0.85 | SREBF2 (0.41) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL16535861 | 0.84 | SREBF2 (0.48) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197235 | 0.84 | SREBF2 (0.42) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197440 | 0.82 | KDM4E (0.36) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197269 | 0.80 | SREBF2 (0.56) | SREBF2MAPTATMKDM4ELMNA | |
| SCHEMBL20197302 | 0.80 | SMN1; SMN2 (0.46) | MAPTATMKDM4ELMNAL3MBTL1 | |
| SCHEMBL20197270 | 0.80 | SREBF2 (0.53) | SREBF2MAPTATMKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |