Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872884 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL20197575 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL18398016 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL17047030 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL872486 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL23437849 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL872193 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL20797268 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL21249045 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL19616579 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327125-A1 | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (SINA) | Sirna Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |