Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872884 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL20197575 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL20197385 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL18398016 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL17047030 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL23437849 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL872193 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL20797268 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL21249045 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP | |
| SCHEMBL19616579 | 1.00 | FAAH (0.48) | FAAHTRPV1SPHK2SPHK1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 816 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240123047-A1 | LIPID NANOPARTICLE ADJUVANT COMPOSITION FOR PNEUMOCOCCAL CONJUGATE VACCINES | MERCK SHARP & DOHME LLC (US) | 2024-04-18 | — | — | US | claimed |
| US-11566051-B2 | Stabilized RSV F proteins and uses thereof | MERCK SHARP & DOHME LLC (US) | 2023-01-31 | — | — | US | claimed |
| US-11413348-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THEREPEUTICS, INC. (US) | 2022-08-16 | — | — | US | claimed |
| EP-3943114-A1 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | Sirna Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | claimed |
| EP-3939604-A2 | INFLUENZA HEMAGGLUTININ PROTEIN VACCINES | Merck Sharp & Dohme Corp. (US) | 2022-01-19 | — | — | EP | claimed |
| US-20210300971-A1 | STABILIZED RSV F PROTEINS AND USES THEREOF | MERCK SHARP & DOHME LLC | 2021-09-30 | — | — | US | claimed |
| EP-3144015-B1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS INC (US) | 2021-06-02 | — | — | EP | claimed |
| US-20200222540-A1 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2020-07-16 | — | — | US | claimed |
| EP-3556353-A2 | LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS | MERCK SHARP & DOHME CORP. (US) | 2019-10-23 | — | — | EP | claimed |
| US-20190314486-A1 | INFLUENZA HEMAGGLUTININ PROTEIN VACCINES | MERCK SHARP & DOHME CORP. (US) | 2019-10-17 | — | — | US | claimed |
| US-20190167811-A1 | LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY | MODERNATX, INC. | 2019-06-06 | — | — | US | claimed |
| EP-3442590-A2 | LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY | Modernatx, Inc. (US) | 2019-02-20 | — | — | EP | claimed |
| US-20180311176-A1 | NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACID COMPLEXES | TRANSLATE BIO MA, INC. (US) | 2018-11-01 | — | — | US | claimed |
| WO-2017192470-A1 | COMBINATION THERAPY OF ANTI-IL-10 ANTIBODY AND COMPOSITIONS COMPRISING LIPID NANOPARTICLES AND TLR9 AGONIST CPG OLIGONUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017180917-A2 | LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY | MODERNATX, INC. (US) | 2017-10-19 | — | — | WO | claimed |
| EP-3144015-A2 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | Sirna Therapeutics, Inc. (US) | 2017-03-22 | — | — | EP | claimed |
| EP-3110401-A2 | LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS | Merck Sharp & Dohme Corp. (US) | 2017-01-04 | — | — | EP | claimed |
| US-20160361411-A1 | LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS | MERCK SHARP & DOHME CORP (US) | 2016-12-15 | — | — | US | claimed |
| WO-2015130584-A2 | LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS | MERCK SHARP & DOHME CORP. (US) | 2015-09-03 | — | — | WO | claimed |
| US-20130178541-A1 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2013-07-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180311176-A1 | NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACID COMPLEXES | DIS3, SYNCRIP, EXOSC5 | FAAH 3759/4885TRPV1 4841/4885SPHK2 3128/4885 |
| US-20160361411-A1 | LIPID NANOPARTICLE VACCINE ADJUVANTS AND ANTIGEN DELIVERY SYSTEMS | TLR3, TLR5, TLR1 | FAAH 955/4885TRPV1 188/4885SPHK2 1038/4885 |
| US-20190167811-A1 | LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY | RNMT, PHOSPHO1, POLM | FAAH 2350/4885TRPV1 3576/4885SPHK2 554/4885 |
| US-20240123047-A1 | LIPID NANOPARTICLE ADJUVANT COMPOSITION FOR PNEUMOCOCCAL CONJUGATE VACCINES | PLTP, NAPEPLD, PHOSPHO1 | FAAH 1516/4885TRPV1 4537/4885SPHK2 1378/4885 |
| US-20130178541-A1 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | LDLR, LIPC, CETP | FAAH 3866/4885TRPV1 3041/4885SPHK2 185/4885 |
| US-20200222540-A1 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | LDLR, APOB, NPC1L1 | FAAH 3408/4885TRPV1 3074/4885SPHK2 252/4885 |
| US-11413348-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | LDLR, APOB, CETP | FAAH 3663/4885TRPV1 3436/4885SPHK2 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.