Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311511 | 0.74 | MCL1 (0.47) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL21307803 | 0.72 | MCL1 (0.45) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL4076704 | 0.71 | HMGCR (0.44) | TSHR | |
| SCHEMBL2730881 | 0.71 | MCL1 (0.48) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL2836345 | 0.71 | MCL1 (0.44) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL25062344 | 0.70 | MCL1 (0.40) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL5987745 | 0.70 | MCL1 (0.47) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL21758993 | 0.69 | MMP2 (0.55) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL6313039 | 0.69 | MCL1 (0.42) | MCL1MMP1MMP2MMP3MMP9 | |
| SCHEMBL20928420 | 0.68 | MCL1 (0.45) | MCL1MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917195-B9 | SPLICEOSTATIN ANALOGS | PFIZER (US) | 2018-05-30 | — | — | EP | disclosed |