Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.55 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.55 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094003 | 0.90 | MGLL (0.53) | MGLLABHD6PLA2G7VEGFAEGLN1 | |
| SCHEMBL15094305 | 0.88 | MGLL (0.51) | MGLLABHD6PLA2G7GPR119MAPT | |
| SCHEMBL15093862 | 0.88 | MGLL (0.52) | MGLLABHD6PLA2G7GPR119MAPT | |
| SCHEMBL16579906 | 0.87 | MGLL (0.52) | MGLLABHD6PLA2G7GPR119VEGFA | |
| SCHEMBL15093849 | 0.86 | MGLL (0.55) | MGLLABHD6PLA2G7GPR119MAPT | |
| SCHEMBL18210853 | 0.86 | SMN1; SMN2 (0.54) | GPR119VEGFAEGLN1MAPTALDH1A1 | |
| SCHEMBL15265138 | 0.84 | HPGD (0.53) | MGLLABHD6PLA2G7VEGFAEGLN1 | |
| SCHEMBL1958222 | 0.84 | MGLL (0.52) | MGLLABHD6PLA2G7GPR119VEGFA | |
| SCHEMBL15100824 | 0.84 | FAAH (0.45) | MGLLABHD6PLA2G7GPR119ALDH1A1 | |
| SCHEMBL30074246 | 0.84 | FAAH (0.45) | MGLLABHD6PLA2G7GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-2800565-B1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |