Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348993 | 0.91 | TRPC3 (0.50) | TRPC3PIM1PIM3PIM2NOTUM | |
| SCHEMBL18064945 | 0.83 | PIM2 (0.62) | PIM1PIM3PIM2NOTUMTDP1 | |
| SCHEMBL18064765 | 0.83 | PIM2 (0.62) | PIM1PIM3PIM2NOTUMTDP1 | |
| SCHEMBL20769603 | 0.81 | PIM1 (0.44) | TRPC3PIM1PIM3PIM2NOTUM | |
| SCHEMBL15094219 | 0.78 | SMPD3 (0.47) | NOTUM | |
| SCHEMBL18064766 | 0.78 | SMO (0.43) | PIM1PIM3PIM2NOTUM | |
| SCHEMBL18861670 | 0.78 | HTT (0.49) | TRPC3PIM1PIM3PIM2NOTUM | |
| SCHEMBL15093884 | 0.77 | ALDH1A3 (0.53) | TDP1MAPTALDH1A1HTTTSHR | |
| SCHEMBL15093842 | 0.77 | NOTUM (0.50) | PIM1PIM3PIM2NOTUMDRD2 | |
| SCHEMBL15266738 | 0.76 | HRH4 (0.51) | PIM1PIM3PIM2POLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |