Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20198169 | 0.91 | TRPC3 (0.45) | TRPC3ALDH1A1HTTGRM5TP53 | |
| SCHEMBL20769603 | 0.86 | PIM1 (0.44) | TRPC3ALDH1A1TDP1POLBMAPT | |
| SCHEMBL20018697 | 0.83 | MAPT (0.49) | ALDH1A1HTTTP53POLBMAPT | |
| SCHEMBL15093884 | 0.82 | ALDH1A3 (0.53) | ALDH1A1HTTTP53TDP1POLB | |
| SCHEMBL26618064 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HTTTP53POLBMAPT | |
| SCHEMBL19582589 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTTP53TDP1POLB | |
| SCHEMBL18064770 | 0.80 | L3MBTL1 (0.62) | ALDH1A1POLBDRD2MAPTHPGD | |
| SCHEMBL20424771 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HTTTP53POLBMAPT | |
| SCHEMBL18064765 | 0.79 | PIM2 (0.62) | TDP1MAPTPIM1PIM3PIM2 | |
| SCHEMBL18064945 | 0.79 | PIM2 (0.62) | TDP1MAPTPIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271352-B1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2021-05-12 | — | — | EP | disclosed |