Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218972 | 0.77 | TDP1 (0.55) | TDP1ERN1ALDH1A1MAPTHPGD | |
| SCHEMBL20198141 | 0.75 | TDP1 (0.46) | TDP1ERN1ALDH1A1MAPTMEN1 | |
| SCHEMBL28299606 | 0.70 | TDP1 (0.55) | TDP1ERN1ALDH1A1MAPTHPGD | |
| SCHEMBL9753459 | 0.69 | TDP1 (0.50) | TDP1ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL2212088 | 0.65 | KMT2A (0.52) | TDP1ERN1ALDH1A1MAPTHPGD | |
| SCHEMBL4357334 | 0.64 | TDP1 (0.70) | TDP1ERN1ALDH1A1MAPTHPGD | |
| SCHEMBL1019524 | 0.63 | ERN1 (0.69) | TDP1ERN1ALDH1A1 | |
| SCHEMBL29062573 | 0.63 | ERN1 (0.52) | TDP1ERN1ALDH1A1HPGDKDM4E | |
| SCHEMBL13810126 | 0.63 | ERN1 (0.57) | TDP1ERN1ALDH1A1KDM4EPTPN1 | |
| SCHEMBL14611052 | 0.62 | CCR2 (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |