Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | ERN1 | O75460 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28578537 | 0.97 | TDP1 (0.67) | TDP1ERN1HSD17B10LMNAMEN1 | |
| SCHEMBL19521144 | 0.86 | TDP1 (0.59) | TDP1ERN1HSD17B10LMNAMEN1 | |
| SCHEMBL19521160 | 0.86 | TDP1 (0.59) | TDP1ERN1HSD17B10PTPN1XDH | |
| SCHEMBL10924784 | 0.86 | TDP1 (0.59) | TDP1ERN1HSD17B10LMNAMEN1 | |
| SCHEMBL789811 | 0.83 | ERN1 (0.57) | TDP1ERN1HSD17B10LMNAKMT2A | |
| SCHEMBL29889164 | 0.82 | TDP1 (1.00) | TDP1ERN1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL95435 | 0.82 | TDP1 (1.00) | TDP1ERN1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL42560 | 0.82 | TDP1 (0.67) | TDP1ERN1HSD17B10PTPN1XDH | |
| Bromide SCHEMBL29952083 | 0.81 | ERN1 (0.55) | TDP1ERN1HSD17B10LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL29956054 | 0.81 | ERN1 (0.55) | TDP1ERN1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481788-B1 | Process for preparing ink jet recording head | CANON KK (JP) | 1997-01-02 | — | — | EP | claimed |
| US-10833274-B2 | Organic semiconductor compositions | SMARTKEM LIMITED (GB) | 2020-11-10 | — | — | US | disclosed |
| EP-2817352-B1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LTD (GB) | 2020-08-26 | — | — | EP | disclosed |
| EP-2817351-B1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LTD (GB) | 2020-08-26 | — | — | EP | disclosed |
| US-20150034878-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2015-02-05 | — | — | US | disclosed |
| US-20150034878-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2015-02-05 | — | — | US | disclosed |
| US-20150021524-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2015-01-22 | — | — | US | disclosed |
| US-20150021524-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2015-01-22 | — | — | US | disclosed |
| WO-2013124684-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013124683-A1 | ORGANIC SEMICONDUCTOR COMPOSITIONS | SMARTKEM LIMITED (GB) | 2013-08-29 | — | — | WO | disclosed |
| EP-1478646-A1 | AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20030236270-A1 | Azabicyclic compounds for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-12-25 | — | — | US | disclosed |
| WO-2003072578-A1 | AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| US-5985913-A | GENE EXPRESSION AND CELL GROWTH FACTORS FOR BIOSYNTHESIS | OSI PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | disclosed |
| US-5334999-A | Device for preparing ink jet recording head with channels containing energy generating elements | CANON KABUSHIKI KAISHA (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0384392-A1 | Cyanation of haloaromatics utilizing catalysts generated in situ starting with NiCl2 or NiCl2 6H2O | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4715993-A | FROM SALTS, USING AMMONIA OR METHYLAMINE | AMERICAN CYANAMID COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| US-4526788-A | Polymeric[[(oxazolidinyl)alkyl]amino]anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0122417-A2 | Polymeric(((oxazolidinyl)alkyl)amino)anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236270-A1 | Azabicyclic compounds for the treatment of disease | MALT1, TPMT, CYP2B6 | TDP1 2620/4885ERN1 2819/4885HSD17B10 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.