SCHEMBL20198184

SCHEMBL20198184

Cc1ccc(-c2ccc(F)cc2)c(C)c1C1CNC2(CCOCC2)C1O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19558864 0.83 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL2054307 0.68 HDAC1 (0.35) HDAC1HDAC2ABL1
SCHEMBL12029758 0.67 HDAC1 (0.32) HDAC1HDAC2HCRTR1HCRTR2
SCHEMBL2361764 0.66 PRKDC (0.36) HDAC1HDAC2
SCHEMBL30414708 0.64 ACACB (0.41) HDAC1HDAC2HCRTR1HCRTR2
SCHEMBL122076 0.64 ACACB (0.41) HDAC1HDAC2HCRTR1HCRTR2
SCHEMBL10079525 0.62 HDAC2 (0.34) HDAC1HDAC2
SCHEMBL18286702 0.60 ACHE (0.39) ABL1
SCHEMBL6113640 0.59 HDAC1 (0.35) HDAC1HDAC2HCRTR1HCRTR2
SCHEMBL21937382 0.58 MEN1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118947730-A Plant treatment products and related methods 美国赛多美科技有限公司 2024-11-15 CN disclosed
CN-110678076-B Plant treatment products and related methods 美国赛多美科技有限公司 2024-07-23 CN disclosed
EP-2099751-B1 BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS BAYER IP GMBH (DE) 2018-05-30 EP disclosed