SCHEMBL122076

SCHEMBL122076

Cc1ccc(-c2ccc(F)cc2)c(C)c1C1=C(O)C2(CCOCC2)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACACB O00763 11/20 0.41
ACACA Q13085 11/20 0.41
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
POLB P06746 1/20 0.32
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
PTGS1 P23219 1/20 0.30
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414708 1.00 ACACB (0.41) ACACBACACAHDAC1HDAC2PDE3B
SCHEMBL25469386 0.92 ACACB (0.41) ACACBACACA
SCHEMBL20941357 0.90 ACACB (0.40) ACACBACACAHDAC1HDAC2PDE3B
SCHEMBL30753926 0.89 ACACB (0.51) ACACBACACA
SCHEMBL290583 0.89 ACACB (0.51) ACACBACACA
SCHEMBL2354596 0.89 ACACB (0.43) ACACBACACAPOLBHCRTR1HCRTR2
SCHEMBL30843018 0.88 ACACB (0.42) ACACBACACAPDE3BPDE3APOLB
SCHEMBL12029913 0.85 ACACB (0.35) ACACBACACAHDAC1HDAC2PDE3B
SCHEMBL12540228 0.85 ACACB (0.49) ACACBACACAPOLB
SCHEMBL12540422 0.85 ACACB (0.49) ACACBACACAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 WO claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP claimed
EP-4618760-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 EP claimed
EP-4618761-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 EP claimed
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 US claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
WO-2024104813-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 EP claimed
US-20120083463-A1 Insecticidal and Fungicidal Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2012-04-05 US claimed
WO-2011157778-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO claimed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US claimed
WO-2011061156-A1 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-05-26 WO claimed
US-20110118115-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-19 US claimed
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 US claimed
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2011-02-24 US claimed
US-20110033432-A1 Combinations of Biological Control Agents and Insecticides BAYER CROPSCIENCE AG (DE) 2011-02-10 US claimed
EP-2269455-A1 Combinations of biological control agents and insecticides Bayer CropScience AG (DE) 2011-01-05 EP claimed
WO-2010149370-A1 COMBINATIONS OF BIOLOGICAL CONTROL AGENTS AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2010-12-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033432-A1 Combinations of Biological Control Agents and Insecticides ACHE, ITPR3, CTRL ACACB 300/4885ACACA 464/4885HDAC1 1988/4885
US-20110118115-A1 Active compound combinations AADAC, ACACA, DDT ACACB 4/4885ACACA 2/4885HDAC1 163/4885
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 ACACB 4286/4885ACACA 4272/4885HDAC1 2158/4885
US-20120083463-A1 Insecticidal and Fungicidal Active Compound Combinations DDT, ACHE, CYP4B1 ACACB 1382/4885ACACA 2104/4885HDAC1 55/4885
US-20110045104-A1 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides ATL3, PDIA3, NAT1 ACACB 97/4885ACACA 120/4885HDAC1 784/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 ACACB 2642/4885ACACA 1705/4885HDAC1 584/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 ACACB 8/4885ACACA 4/4885HDAC1 26/4885
US-20110046194-A1 3-Triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides CYP4B1, ARSA, C1S ACACB 50/4885ACACA 95/4885HDAC1 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.