Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211744 | 0.88 | KDM4E (0.52) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL21644162 | 0.87 | KDM4E (0.55) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL18579955 | 0.86 | ROCK1 (0.53) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL428922 | 0.86 | CYP2A13 (0.50) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL3264221 | 0.85 | ROCK1 (0.49) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL3264764 | 0.85 | ROCK1 (0.52) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL20680449 | 0.83 | ROCK1 (0.47) | ROCK1KDM4ESMN1; SMN2LPLLIPG | |
| SCHEMBL2798956 | 0.83 | ROCK1 (0.50) | ROCK1KDM4ESMN1; SMN2LMNACYP1A2 | |
| SCHEMBL13517081 | 0.81 | ROCK1 (0.48) | ROCK1KDM4ESMN1; SMN2LMNALPL | |
| SCHEMBL3263593 | 0.81 | ROCK1 (0.50) | ROCK1KDM4ESMN1; SMN2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |