Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963721 | 0.86 | LMNA (0.54) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL29022807 | 0.86 | LMNA (0.54) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL3299759 | 0.86 | FLT1 (0.65) | LMNAHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL15087952 | 0.85 | LMNA (0.62) | LMNAHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL15500985 | 0.83 | LMNA (0.51) | KDM4ELMNAHPGDALDH1A1NPC1 | |
| SCHEMBL120129 | 0.83 | KCNA3 (0.52) | LMNAHPGDNPC1RAB9AKMT2A | |
| SCHEMBL3655826 | 0.83 | KCNA3 (0.52) | LMNAHPGDNPC1RAB9AKMT2A | |
| SCHEMBL29687002 | 0.83 | KCNA3 (0.52) | LMNAHPGDNPC1RAB9AKMT2A | |
| SCHEMBL28864011 | 0.81 | FLT1 (0.61) | LMNAALDH1A1RAB9AHTTKMT2A | |
| SCHEMBL31249658 | 0.80 | HSD17B10 (0.53) | LMNAHPGDALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |