Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 9/20 | 0.65 |
| ▸ | FLT4 | P35916 | 9/20 | 0.65 |
| ▸ | KDR | P35968 | 9/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864011 | 0.94 | FLT1 (0.61) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL20198202 | 0.86 | KDM4E (0.63) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL29963721 | 0.85 | LMNA (0.54) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL29022807 | 0.85 | LMNA (0.54) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL15087952 | 0.84 | LMNA (0.62) | FLT1FLT4KDRLMNAL3MBTL1 | |
| SCHEMBL15500985 | 0.82 | LMNA (0.51) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL120129 | 0.82 | KCNA3 (0.52) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL29687002 | 0.82 | KCNA3 (0.52) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL3655826 | 0.82 | KCNA3 (0.52) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL3306626 | 0.81 | FLT1 (0.76) | FLT1FLT4KDRL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119699-B1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER IP GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-8236986-B2 | Process for preparing acylsulfamoylbenzamides | BAYER CROPSCIENCE GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-2119699-A1 | Process for preparing acylsulfamoylbenzamides | Bayer CropScience AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| US-7608736-B2 | Chlorination a a benzenesulfamoyl compound in presence of a base | BAYER CROPSCIENCE GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| EP-1644324-B1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-30 | — | — | EP | disclosed |
| EP-1644324-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | Bayer CropScience GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | US | disclosed |
| WO-2005000797-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094052-A1 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES | SULT2A1, STS, SULT1A1 | FLT1 3530/4885FLT4 3664/4885KDR 4150/4885 |
| US-20050004372-A1 | Process for preparing acylsulfamoylbenzamides | SULT2A1, STS, SULT1A1 | FLT1 3530/4885FLT4 3664/4885KDR 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.