Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 17/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742443 | 0.90 | PDK2 (0.44) | PDK2 | |
| SCHEMBL20420088 | 0.81 | PDK2 (0.46) | PDK2ESR1ESR2 | |
| SCHEMBL15041018 | 0.81 | PDK2 (0.47) | PDK2 | |
| SCHEMBL134286 | 0.81 | PDK2 (0.58) | PDK2 | |
| SCHEMBL134285 | 0.81 | PDK2 (0.58) | PDK2 | |
| SCHEMBL29114 | 0.81 | PDK2 (0.58) | PDK2 | |
| SCHEMBL12856554 | 0.81 | PDK2 (0.41) | PDK2ESR1ESR2KDM4EMEN1 | |
| SCHEMBL2456262 | 0.79 | PDK2 (0.55) | PDK2KMT2A | |
| SCHEMBL5846670 | 0.79 | PDK2 (0.55) | PDK2KMT2A | |
| SCHEMBL12337045 | 0.79 | PDK2 (0.60) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |